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A <i>Drosophila</i> RNAi screen reveals conserved glioblastoma-related adhesion genes that regulate collective cell migration

2021-08-09

Abstract excerpt

<h4>ABSTRACT</h4> Migrating cell collectives are key to embryonic development but also contribute to invasion and metastasis of a variety of cancers. Cell collectives can invade deep into tissues, leading to tumor progression and resistance to therapies. Collective cell invasion is also observed in the lethal brain tumor glioblastoma, which infiltrates the surrounding brain parenchyma leading to tumor growth and...

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Literature Corpus work
15bfe8d7-5421-52a6-be4c-44a04e957d52
DOI
10.1101/2021.08.09.455704
Open publication

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A <i>Drosophila</i> RNAi screen reveals conserved glioblastoma-related adhesion genes that regulate collective cell migrationDOI 10.1101/2021.08.09.455704
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