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Identifying conserved molecular targets required for cell migration of glioblastoma cancer stem cells

26 Feb 2020

Abstract excerpt

Glioblastoma (GBM) is the most prevalent primary malignant brain tumor and is associated with extensive tumor cell infiltration into the adjacent brain parenchyma. However, there are limited targeted therapies that address this disease hallmark. While the invasive capacity of self-renewing cancer stem cells (CSCs) and their non-CSC progeny has been investigated, the mode(s) of migration used by CSCs during...

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PMID: 32102991
DOI: 10.1038/s41419-020-2342-2

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