Article

Resveratrol alleviated 5-FU-induced cardiotoxicity by attenuating GPX4 dependent ferroptosis

2024-01-31

Abstract excerpt

<h4>Purpose: </h4> The clinical use of 5-fluorouracil (5-FU), a potent antitumor agent, was limited by severe cardiotoxic effects. The present study was aimed to investigate the protective effects of resveratrol (Res) on 5-FU-induced cardiotoxicity and to explore its potential mechanisms. <h4>Methods:</h4> The cardiotoxicity model was intraperitoneal injection of 5-FU at the dose of 30 mg/kg for 7 consecutive days...

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Literature Corpus work: 15a65dd4-25ad-5caf-a090-61dbadf2578c
DOI: 10.22541/au.170670199.96721840/v1

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