Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipid Peroxidation and GPX4 Inhibition Are Common Causes for Myofibroblast Differentiation and Ferroptosis

29 May 2019

Abstract excerpt

Ferroptosis is a new form of regulated cell death. Fibroblast-to-myofibroblast differentiation is known to be involved in the pathogenesis of idiopathic pulmonary fibrosis. Utilizing HFL1 cell line treated with transforming growth factor-β1 (TGF-β1), we investigated the relationship between ferroptosis and pulmonary fibrosis, and the function of glutathione peroxidase 4 (GPX4) in them. The results indicated that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Medical Imaging and Pathology Studies
Share to Pulmonary Hypertension Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31140862
DOI: 10.1089/dna.2018.4541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipid Peroxidation and GPX4 Inhibition Are Common Causes for Myofibroblast Differentiation and FerroptosisPMID 31140862Read ↗

Physiological Effects of Ferroptosis on Organ FibrosisSemantic proximity Read ↗

Molecular Mechanisms of Ferroptosis and Its Role in Pulmonary DiseaseSemantic proximity Read ↗

A deep insight into ferroptosis in lung disease: facts and perspectivesSemantic proximity Read ↗

New insights into crosstalk between Nrf2 pathway and ferroptosis in lung diseaseSemantic proximity Read ↗

Ferroptosis and EMT: key targets for combating cancer progression and therapy resistanceSemantic proximity Read ↗

Application of natural products for inducing ferroptosis in tumor cellsSemantic proximity Read ↗

The emerging role of ferroptosis in inflammationSemantic proximity Read ↗

Quercetin and FerroptosisSemantic proximity Read ↗

Ferroptosis and renal fibrosis: A new target for the future (Review)Semantic proximity Read ↗

Ferroptosis: From regulation of lipid peroxidation to the treatment of diseasesSemantic proximity Read ↗

GPX4, ferroptosis, and diseasesSemantic proximity Read ↗

Nrf2-mediated ferroptosis inhibition: a novel approach for managing inflammatory diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.