Article

Lancet: genome-wide somatic variant calling using localized colored DeBruijn graphs

2017-09-30

Abstract excerpt

Reliable detection of somatic variations is of critical importance in cancer research. Lancet is an accurate and sensitive somatic variant caller which detects SNVs and indels by jointly analyzing reads from tumor and matched normal samples using colored DeBruijn graphs. Extensive experimental comparison on synthetic and real whole-genome sequencing datasets demonstrates that Lancet has better accuracy, especially...

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Literature Corpus work: 1594e388-90b4-5dc2-afee-30b131b6bd4d
DOI: 10.1101/196311

Open publication

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