Article

A mechanistic model for genetic regulation of postmenopausal bone loss

2026-06-08

Abstract excerpt

Bone remodeling is a tightly regulated physiological process that maintains bone health through coordinated action of bone-resorbing osteoclasts and bone-forming osteoblasts. Disruption of this balance, such as the one induced by estrogen decline after menopause, results in bone loss and osteoporosis. Genetic factors play an important role in determining bone mineral density (BMD) loss over time. However, translat...

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Literature Corpus work: 157796c9-4490-585b-a01b-62f6611392f7
DOI: 10.64898/2026.06.04.26354968

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