Article
Genetic contributors to osteoporosis in pregnancy and lactation associated osteoporosis (PLO).
Bone - 1 Mar 2026
Lynch Lauren, Shea Patrick R, Vena Natalie, Chung Wendy K, Shane Elizabeth, Kamanda-Kosseh Mafo, Barry Jordan, El-Najjar Dany, Agarwal Sanchita, Kondapalli Ananya, Colon Ivelisse, Bucovsky Mariana, Cohen Adi
Abstract excerpt
Pregnancy- and lactation-associated osteoporosis (PLO) describes a fragility fracture presentation around pregnancy/lactation. Presentation often includes multiple vertebral fractures, but can also involve hip, sacral/pelvic, or other fractures. Substantial bone structural deficits and low bone formation rate have been documented. Most have no known secondary cause. Many have a history of childhood fracture...
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