Article

h-channels contribute to divergent electrophysiological properties of supragranular pyramidal neurons in human versus mouse cerebral cortex

2018-05-02

Abstract excerpt

<h4>Summary</h4> Gene expression studies suggest that differential ion channel expression contributes to differences in rodent versus human neuronal physiology. We tested whether h-channels more prominently contribute to the physiological properties of human compared to mouse supragranular pyramidal neurons. Single cell/nucleus RNA sequencing revealed ubiquitous HCN1-subunit expression in excitatory neurons in hu...

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Literature Corpus work: 70188507-a548-5d1a-8810-4e820947ad64
DOI: 10.1101/312298

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