Article

STAT6 blockade ameliorates thyroid function in Graves' disease via downregulation of the Sodium/Iodide Symporter

2024-02-12

Abstract excerpt

<h4>Background: </h4> Signal Transducer and Activator of Transcription 6 (STAT6) is an important nuclear transcription factor. Previous study demonstrated that blockading STAT6 can ameliorate thyroid function by reducing serum T3 and T4. Sodium/iodide symporter (NIS) is a key protein that mediates active iodine uptake and plays an important role in regulating thyroid function. This study explored the interaction b...

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Literature Corpus work: 15571c37-a4fa-5f45-a080-53b8e28dc20e
DOI: 10.21203/rs.3.rs-3936891/v1

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