Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The sodium iodide symporter: its pathophysiological and therapeutic implications.

Clinical endocrinology - 1 Nov 2002

Spitzweg Christine, Morris John C

Abstract excerpt

The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates the active transport of iodide in the thyroid gland and a number of extrathyroidal tissues, in particular lactating mammary gland. Because of its crucial role in the ability of thyroid follicular cells to trap iodide, cloning of NIS opened an exciting and extensive new field of thyroid-related research. Cloning and molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport, Active
Share to Breast
Share to Carcinoma, Papillary, Follicular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Iodine

Share to Thyroid Diseases

Share to Thyroid Gland

Share to Thyroiditis, Autoimmune

Share to Tretinoin

Source

Identifiers

PMID: 12390328
DOI: 10.1046/j.1365-2265.2002.01640.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The sodium iodide symporter: its pathophysiological and therapeutic implications.PMID 12390328Read ↗

The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance.Semantic proximity Read ↗

The sodium iodide symporter (NIS): novel applications for radionuclide imaging and treatmentSemantic proximity Read ↗

Sodium Iodide Symporter for Nuclear Molecular Imaging and Gene Therapy: From Bedside to Bench and BackSemantic proximity Read ↗

The sodium iodide symporter: its emerging relevance to clinical thyroidology.Semantic proximity Read ↗

The Biology of the Sodium Iodide Symporter and its Potential for Targeted Gene DeliverySemantic proximity Read ↗

Radioiodine Therapy in Differentiated Thyroid Cancer: The First Targeted Therapy in OncologySemantic proximity Read ↗

[Sodium-iodine symporter of the thyroid gland. Discovery, characterization, clinical relevance and prospects].Semantic proximity Read ↗

Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism.Semantic proximity Read ↗

A homozygous missense mutation of the sodium/iodide symporter gene causing iodide transport defect.Semantic proximity Read ↗

Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapySemantic proximity Read ↗

Brief Report: A Novel Sodium/Iodide Symporter Mutation, S356F, Causing Congenital Hypothyroidism.Semantic proximity Read ↗

New mechanisms of radioiodide uptake revealed via a novel high throughput drug screening approach in thyroid cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.