Article
Graves' IgG activate upstream enhancer of the sodium/iodide symporter.
Molecular and cellular endocrinology - 31 Dec 2003
Breous Ekaterina, Wenzel Achim, Loos Ulrich
Abstract excerpt
Graves' thyroid tissue has been shown to express elevated levels of human sodium/iodide symporter (hNIS) mRNA and protein. In the present work, we demonstrate for the first time that hNIS gene expression in Graves' disease (GD) is up-regulated by Graves' IgG. Here, in transient transfection exper...
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