Article
Phytochemicals for the Management of Melanoma.
Mini reviews in medicinal chemistry - 1 Jan 2016
Pal Harish Chandra, Hunt Katherine Marchiony, Diamond Ariana, Elmets Craig A, Afaq Farrukh
Abstract excerpt
Melanoma claims approximately 80% of skin cancer-related deaths. Its life-threatening nature is primarily due to a propensity to metastasize. The prognosis for melanoma patients with distal metastasis is bleak, with median survival of six months even with the latest available treatments. The most commonly mutated oncogenes in melanoma are BRAF and NRAS accounting approximately 60% and 20% of cases, respectively....
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