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Deep oncopanel sequencing reveals fixation time- and within block position-dependent quality degradation in FFPE processed samples

2021-04-07

Abstract excerpt

Clinical laboratories routinely use formalin-fixed paraffin-embedded (FFPE) tissue or cell block cytology samples in oncology panel sequencing to identify mutations that can predict patient response to targeted therapy. To understand the technical error due to FFPE processing, a robustly characterized normal cell line was used to create FFPE samples with four different pre-tissue processing formalin fixation times...

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Literature Corpus work
14cf0402-9674-5f4a-9953-7b25f436c92c
DOI
10.1101/2021.04.06.438687
Open publication

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Deep oncopanel sequencing reveals fixation time- and within block position-dependent quality degradation in FFPE processed samplesDOI 10.1101/2021.04.06.438687
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