Article
Advantage of the F(ab)’2 fragment over IgG for RIT and PRIT
2024-10-17
Abstract excerpt
Radioimmunotherapy (RIT) has proved clinically effective in the treatment of relapsed or consolidating NHL after chemotherapy. However, it is still at the clinical trial stage for the treatment of solid tumors. The efficacy of the treatment on this type of tumor is limited by hematological toxicity, which restricts the activities injected. Pre-targeted radioimmunotherapy (PRIT) enables radiolabeling to be carried...
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Identifiers and source
- Literature Corpus work
- 145446a1-3251-50bb-9ac9-a61ca75318dc
- DOI
- 10.1101/2024.10.16.617029
