Article

Targeted therapy of breast cancer using PLAC1 antibody-drug conjugate

2023-12-29

Abstract excerpt

<h4>Background: </h4> Placenta-specific 1 (PLAC1) is one of the oncoplacental genes ectopically expressed in a wide variety of cancers. Antibody drug conjugates (ADC) have the potential to substantially improve efficacy and reduce toxicity of treatment compared with cytotoxic small-molecule drugs and are recently being employed for treatment of cancers. Here, efficacy of a SN38-conjugated monoclonal anti-PLAC1 ant...

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Literature Corpus work: 327f6c23-b480-579d-a1fc-35e65421f8f2
DOI: 10.21203/rs.3.rs-3801644/v1

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