Article

Individual cell fate and population dynamics revealed by a mathematical model linking telomere length and replicative senescence

2023-11-22

Abstract excerpt

Progressive shortening of telomeres ultimately causes replicative senescence and is linked with aging and tumor suppression. Studying the intricate link between telomere shortening and senescence at the molecular level and its population-scale effects over time is challenging with current approaches but crucial for understanding behavior at the organ or tissue level. In this study, we developed a mathematical mode...

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Identifiers and source

Literature Corpus work: 145393fb-7236-5004-ab13-be3ded9723ed
DOI: 10.1101/2023.11.22.568287

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