Article

Expanded polyQ aggregates interact with Sarco-endoplasmic reticulum calcium ATPase and Drosophila Inhibitor of Apoptosis Protein1 to regulate polyQ mediated neurodegeneration in Drosophila

2023-02-02

Abstract excerpt

<title>Abstract</title> Polyglutamine (polyQ) induced neurodegeneration is one of the leading causes of progressive neurodegenerative disorders characterized clinically by deteriorating movement defects, psychiatric disability, and dementia. Calcium [Ca2+] homeostasis, which is essential for the functioning of neuronal cells, is disrupted under these pathological conditions. In this paper, we simula...

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Literature Corpus work: 142965f7-8ef9-578a-9b9e-ff229747f900
DOI: 10.21203/rs.3.rs-2522400/v1

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Expanded polyQ aggregates interact with Sarco-endoplasmic reticulum calcium ATPase and Drosophila Inhibitor of Apoptosis Protein1 to regulate polyQ mediated neurodegeneration in DrosophilaDOI 10.21203/rs.3.rs-2522400/v1Read

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