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Article

“Plasma Membrane Calcium Atpase downregulation in dopaminergic neurons alters cellular physiology and behavior in Drosophila melanogaster”

2019-07-25

Abstract excerpt

Accumulation of calcium is proposed to account for selective dopaminergic neuron (DN) dysfunctionality, a characteristic of Parkinson’s Disease (PD). To test the in vivo impact of calcium increment in DN physiology we downregulated the Plasma Membrane Calcium ATPase (PMCA), a bomb that extrudes cytosolic calcium, in those neurons in Drosophila melanogaster. Using th -GAL4>PMCA RNAi , PMCA was selectively reduc...

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Literature Corpus work
6b956368-af90-55c0-87d2-2827571629ad
DOI
10.1101/714147
Open publication

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“Plasma Membrane Calcium Atpase downregulation in dopaminergic neurons alters cellular physiology and behavior in Drosophila melanogaster”DOI 10.1101/714147
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