Article

Lipid profiles in the cerebrospinal fluid of rats with 6-hydroxydopamine-induced lesions as a model of Parkinson's disease

2022-09-30

Abstract excerpt

<h4>Background: </h4> Parkinson's disease (PD) is a progressive neurodegenerative disease with characteristic pathological abnormalities, including the loss of dopaminergic (DA) neurons, a dopamine-depleted striatum, and microglial activation. Lipid accumulation exhibits a close relationship with these pathologies in PD. Few studies on PD have focused on the lipid profile of cerebrospinal fluid (CSF), which may re...

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Literature Corpus work: 8760f82e-ccbf-5c31-92a5-872a3938daf5
DOI: 10.21203/rs.3.rs-2098905/v1

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