Article

A Decade of Molecular Preimplantation Genetic Diagnosis of 350 Blastomeres for Beta-Thalassemia Combined with HLA Typing, Aneuploidy Screening and Sex Selection in Iran

2021-12-30

Abstract excerpt

<h4>Background: </h4> Preimplantation genetic diagnosis (PGD) has been developed to detect genetic disorders before pregnancy which is usually done on blastomeres biopsied from 8-cell stage embryos obtained from in vitro fertilization method (IVF).Here we report molecular PGD results for diagnosing of beta thalassemia (beta-thal) which are usually accompanied with evaluating chromosomal aneuploidies, HLA typing an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1414e0db-96d5-558c-8b22-0c5e6115db91
DOI: 10.21203/rs.3.rs-1182982/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Decade of Molecular Preimplantation Genetic Diagnosis of 350 Blastomeres for Beta-Thalassemia Combined with HLA Typing, Aneuploidy Screening and Sex Selection in IranDOI 10.21203/rs.3.rs-1182982/v1Read

Clinical utility of combined preimplantation genetic testing methods in couples at risk of passing on beta thalassemia/hemoglobin E disease: A retrospective review from a single center.Semantic proximity Read

Hemoglobinopathies and preimplantation diagnosticsSemantic proximity Read

Preimplantation Genetic Testing for Thalassemia Through Next- Generation Sequencing of Affected-embryosSemantic proximity Read

Characterizing a cohort of α-thalassemia couples collected during screening for hemoglobinopathies: 14 years of an Iranian experience.Semantic proximity Read

Prenatal and preimplantation diagnosis of hemoglobinopathiesSemantic proximity Read

[Application of NGS-based SNP haplotyping for preimplantation genetic diagnosis for beta-thalassemia and HLA matching].Semantic proximity Read

[Preimplantation Genetic Diagnosis of α/β Complex Thalassemia by Next Generation Sequencing].Semantic proximity Read

Preimplantation genetic diagnosis for hemoglobinopathies.Semantic proximity Read

[Preimplantation genetic diagnosis for carriers of thalassemia and chromosomal abnormality].Semantic proximity Read

Preimplantation Genetic Diagnosis and SelectionSemantic proximity Read

Development of pre-implantation genetic testing protocol for monogenic disorders (PGT-M) of Hb H disease.Semantic proximity Read

Prenatal molecular diagnosis of beta-thalassemia: report on the first two cases in Romania.Semantic proximity Read