Article
Characterizing a cohort of α-thalassemia couples collected during screening for hemoglobinopathies: 14 years of an Iranian experience.
Hemoglobin - 1 Jan 2014
Hafezi-Nejad Nima, Khosravi Mohsen, Bayat Nooshin, Kariminejad Ariana, Hadavi Valeh, Oberkanins Christian, Azarkeivan Azita, Najmabadi Hossein
Abstract excerpt
Our study aimed to determine the number of couples with normal hemoglobin (Hb) electrophoresis and low-borderline hematological values, which may come up with a clinically critical status in their offspring. The number of couples at risk for severe α-thalassemia (α-thal) needed to be estimated before recommending genetic counseling and prenatal diagnosis (PND). During the past 14 years, from at least 7000...
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