Article
Clinical utility of combined preimplantation genetic testing methods in couples at risk of passing on beta thalassemia/hemoglobin E disease: A retrospective review from a single center.
PloS one - 1 Jan 2019
Satirapod Chonthicha, Sukprasert Matchuporn, Panthan Bhakbhoom, Charoenyingwattana Angkana, Chitayanan Pawares, Chantratita Wasun, Choktanasiri Wicharn, Trachoo Objoon, Hongeng Suradej
Abstract excerpt
Thalassemia and hemoglobinopathy is a group of hereditary blood disorder with diverse clinical manifestation inherited by autosomal recessive manner. The Beta thalassemia/Hemoglobin E disease (HbE/βthal) causes a variable degree of hemolysis and the most severe form of HbE/βthal disease develop a lifelong transfusion-dependent anemia. Preimplantation genetic testing (PGT) is an established procedure of embryo...
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