Article

Formation of amyloid fibrils by the regulatory 14-3-3ζ protein

2023-06-02

Abstract excerpt

The 14-3-3 is a highly conserved adaptor protein family with multi-layer functions, abundantly expressed in the brain. The 14-3-3 proteins modulate phosphorylation, regulate enzymatic activity and can act as chaperones. Most importantly, they play an important role in various neurodegenerative disorders due to their vast interaction partners. Particularly, the 14-3-3ξ isoform is known to co-localize in aggregation...

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Literature Corpus work: 140aa7d0-8e95-50cc-baf2-eaf6775cdc7f
DOI: 10.1101/2023.05.31.543065

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