Article
Myelodysplastic syndromes: molecular pathogenesis and genomic changes.
Annals of hematology - 1 Oct 2008
Nolte Florian, Hofmann Wolf-K
Abstract excerpt
Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis presenting with peripheral cytopenias in combination with a hyperplastic bone marrow and an increased risk of evolution to acute myeloid leukemia. The classification systems such as the WHO classification mainly rely on morphological criteria and are supplemented by the International Prognostic Scoring System which takes cytogenetical...
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