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Article

Establishment and characterization of novel patient-derived osteosarcoma xenograft and cell line.

In vitro cellular & developmental biology. Animal - 1 Aug 2018

Kito Fusako, Oyama Rieko, Sakumoto Marimu, Takahashi Mami, Shiozawa Kumiko, Qiao Zhiwei, Sakamoto Hiromi, Hirose Takeshi, Setsu Nokitaka, Yoshida Akihiko, Kawai Akira, Kondo Tadashi

Abstract excerpt

Osteosarcoma is an aggressive mesenchymal malignancy of the bone. Patient-derived models are essential tools for elucidating the molecular mechanisms associated with poor prognosis and the development of novel anticancer drugs. This study described the establishment of a patient-derived cancer model of osteosarcoma. Primary osteosarcoma tumor tissues were obtained from an osteosarcoma patient and inoculated in...

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PMID: 29943355
DOI: 10.1007/s11626-018-0274-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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