Article
Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic.
Molecular biology of the cell - 1 Oct 2005
Volpicelli-Daley Laura A, Li Yawei, Zhang Chun-Jiang, Kahn Richard A
Abstract excerpt
The ADP-ribosylation factors (Arfs) are six proteins within the larger Arf family and Ras superfamily that regulate membrane traffic. Arfs all share numerous biochemical activities and have very similar specific activities. The use of dominant mutants and brefeldin A has been important to the discovery of the cellular functions of Arfs but lack specificity between Arf isoforms. We developed small interference RNA...
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