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A systems-approach to NAD+ restoration

5 Feb 2022

Abstract excerpt

A decline in NAD+ is a feature of ageing and may play a causal role in the process. NAD+ plays a pivotal role in myriad processes important in cellular metabolism and is a cosubstrate for enzymes that play key roles in pathways that modify ageing. Thus, interventions that increase NAD+ may slow aspects of the ageing trajectory and there is great interest in pharmacological NAD+ restoration. Dietary...

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PMID: 35134387
DOI: 10.1016/j.bcp.2022.114946

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