Article
Mitochondrial-derived Peptides: Are They Actually Important?
2023-06-26
Abstract excerpt
Mitochondrial-derived peptides are encoded by mitochondrial DNA but have biological activity outside mitochondria. Eight of these are encoded by sequences within the mitochondrial 12S and 16S ribosomal genes: humanin, MOTS-c, and the six SHLP peptides, SHLP1-SHLP6. These peptides have various effects in cell culture and animal models, affecting neuroprotection, insulin sensitivity, and apoptosis, and some are secr...
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Identifiers and source
- Literature Corpus work
- 1367200c-716a-5691-814d-d2ab0b0e161d
- DOI
- 10.21203/rs.3.rs-3039857/v1