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Mitochondrial-Derived Peptides in Diabetes and Its Complications

3 Feb 2022

Abstract excerpt

The changes of mitochondrial function are closely related to diabetes and its complications. Here we describe the effects of mitochondrial-derived peptides (MDPs), short peptides formed by transcription and translation of the open reading frame site in human mitochondrial DNA (mtDNA), on diabetes and its complications. We mainly focus on MDPs that have been discovered so far, such as Humanin (HN), mitochondrial...

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PMID: 35185787
DOI: 10.3389/fendo.2021.808120

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