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Article

MOTS-c Functionally Prevents Metabolic Disorders

13 Jan 2023

Abstract excerpt

Mitochondrial-derived peptides are a family of peptides encoded by short open reading frames in the mitochondrial genome, which have regulatory effects on mitochondrial functions, gene expression, and metabolic homeostasis of the body. As a new member of the mitochondrial-derived peptide family, mitochondrial open reading frame of the 12S rRNA-c (MOTS-c) is regarding a peptide hormone that could reduce insulin...

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PMID: 36677050
DOI: 10.3390/metabo13010125

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