Article

Phylogenetic expression profiling reveals widespread coordinated evolution of gene expression

2016-03-22

Abstract excerpt

Phylogenetic profiling, which infers functional relationships between genes based on patterns of gene presence/absence across species, has proven to be highly effective. Here we introduce a complementary approach, phylogenetic expression profiling (PEP), which detects gene sets with correlated expression levels across a phylogeny. Applying PEP to RNA-seq data consisting of 657 samples from 309 diverse unicellular...

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Literature Corpus work: 132b44bf-5619-5a1c-b615-dcf9bd62b2ab
DOI: 10.1101/045211

Open publication

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