Article

Dual Epitope Engagement Enables Broad-Spectrum Neutralization of SARS-CoV-2 Variants by Bispecific Antibody 9A6-6C3

2025-10-15

Abstract excerpt

<title>Abstract</title> <p>Given the continuously mutating nature of SARS-CoV-2, the sensitivity of most monoclonal therapeutic antibodies has decreased to the mutants. Bispecific antibodies (BsAbs), with their unique antiviral mechanisms that enable simultaneous binding to two epitopes, offer a distinct advantage in combating the continuous viral mutation by preventing immune escape and enhancing viral neutraliz...

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Literature Corpus work: 132721d8-627e-54e1-b358-8d293593f571
DOI: 10.21203/rs.3.rs-7686776/v1

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