Article
An antibody cocktail with broadened mutational resistance and effective protection against SARS-CoV-2.
Science China. Life sciences - 1 Jan 2023
Sun Chunyun, Chi Hang, Yuan Fei, Li Jing, Yang Ji, Zheng Aihua, Wang Fei, Sun Lingling, Zhang Yanjing, Hu Ping, Jiao Lihua, Deng Yongqiang, Xie Liangzhi
Abstract excerpt
Neutralizing antibodies have been proven to be highly effective in treating mild and moderate COVID-19 patients, but continuous emergence of SARS-CoV-2 variants poses significant challenges. Antibody cocktail treatments reduce the risk of escape mutants and resistance. In this study, a new cocktail composed of two highly potent neutralizing antibodies (HB27 and H89Y) was developed, whose binding epitope is...
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