Article
CD4+ T Cell Dependent B Cell Recovery and Function After Autologous Hematopoietic Stem Cell Transplantation.
Frontiers in immunology - 1 Jan 2021
Heck Clarissa, Steiner Sophie, Kaebisch Eva M, Frentsch Marco, Wittenbecher Friedrich, Scheibenbogen Carmen, Hanitsch Leif G, Nogai Axel, le Coutre Philipp, Bullinger Lars, Blau Igor-Wolfgang, Na Il-Kang
Abstract excerpt
Introduction: High-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto-HSCT) represents a standard treatment regime for multiple myeloma (MM) patients. Common and potentially fatal side effects after auto-HSCT are infections due to a severely compromised immune system with hampered humoral and cellular immunity. This study delineates in depth the quantitative and functional B...
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