Back to search

Article

Brain transcriptomic signatures for mood disorders and suicide phenotypes: an anterior insula and subgenual ACC network postmortem study

2024-08-16

Abstract excerpt

<h4>ABSTRACT</h4> Mood disorders affect over ten percent of humans, but studies dissecting the brain anatomical and molecular neurobiological mechanisms underlying mood (dys)functions have not consistently identified the patterns of pathological changes in relevant brain regions. Recent studies have identified pathological changes in the anterior insula (Ant-Ins) and subgenual anterior cingulate (sgACC) brain net...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
22e2e400-fe97-5d4c-853e-868ac7f039a5
DOI
10.1101/2024.08.14.606080
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Brain transcriptomic signatures for mood disorders and suicide phenotypes: an anterior insula and subgenual ACC network postmortem studyDOI 10.1101/2024.08.14.606080
Neuro-transcriptomic signatures for mood disorder morbidity and suicide mortalitySemantic proximity
Brain network and blood transcriptomic correlations underpin psychopathological phenotypes: A Preliminary StudySemantic proximity
Transcription factor motifs associated with anterior insula gene-expression underlying mood disorder phenotypesSemantic proximity
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals disorder-specific expression changes in major psychiatric disordersSemantic proximity
Transcriptomic analysis uncovers the shared and unique biological foundations acrossSchizophrenia, Bipolar and Major Depressive DisordersSemantic proximity
Post-mortem molecular profiling of three psychiatric disordersSemantic proximity
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathwaysSemantic proximity
Unique Transcriptional Signatures Correlate with Behavioral and Psychological Symptom Domains in Alzheimer’s DiseaseSemantic proximity
Transcriptome sequencing implicates dorsal striatum-specific gene network, immune response and energy metabolism pathways in bipolar disorder.Semantic proximity
Functional Architecture of Brain and Blood Transcriptome Delineate Biological Continuity Between Suicidal Ideation and SuicideSemantic proximity
Post-mortem molecular profiling of three psychiatric disordersSemantic proximity
Molecular Characterization of Depression Trait and StateSemantic proximity
Select a neighboring publication to make it the new centre.