Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness.

Translational psychiatry - 4 Mar 2014

Kohen R, Dobra A, Tracy J H, Haugen E

Abstract excerpt

This study is, to the best of our knowledge, the first application of whole transcriptome sequencing (RNA-seq) to cells isolated from postmortem human brain by laser capture microdissection. We investigated the transcriptome of dentate gyrus (DG) granule cells in postmortem human hippocampus in 79 subjects with mental illness (schizophrenia, bipolar disorder, major depression) and nonpsychiatric controls. We show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Depressive Disorder, Major
Share to Bipolar Disorder
Share to Dentate Gyrus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Laser Capture Microdissection

Share to MicroRNAs

Share to Schizophrenia

Share to Tissue Banks

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 24594777
DOI: 10.1038/tp.2014.9
PMCID: PMC3966046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness.PMID 24594777Read ↗

Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk.Semantic proximity Read ↗

Cell type-specific genetic regulation of expression in the granule cell layer of the human dentate gyrusSemantic proximity Read ↗

Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals disorder-specific expression changes in major psychiatric disordersSemantic proximity Read ↗

Post-mortem molecular profiling of three psychiatric disordersSemantic proximity Read ↗

Post-mortem molecular profiling of three psychiatric disordersSemantic proximity Read ↗

Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosisSemantic proximity Read ↗

Altered MicroRNA Expression Profiles in Postmortem Brain Samples from Individuals with Schizophrenia and Bipolar DisorderSemantic proximity Read ↗

Analysis of induced pluripotent stem cells carrying 22q11.2 deletion.Semantic proximity Read ↗

Single-nucleus RNA sequencing of the midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypesSemantic proximity Read ↗

Transcriptome study of differential expression in schizophrenia.Semantic proximity Read ↗

Transcriptome profiling as a biological marker for bipolar disorder sub-phenotypes.Semantic proximity Read ↗

Neuro-transcriptomic signatures for mood disorder morbidity and suicide mortalitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.