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Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysis

2024-11-21

Abstract excerpt

The assay for transposase-accessible chromatin using sequencing (ATAC-seq) revolutionized the field of epigenetics since its emergence by providing a means to uncover chromatin dynamics and other factors affecting gene expression. The development of single-cell (sc) applications in recent years led to an even deeper understanding of cell type specific gene regulatory mechanisms. One of the major challenges while r...

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Literature Corpus work
12e8b2fa-7efa-57fc-9b12-8770be7e2653
DOI
10.1101/2024.11.20.624480
Open publication

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Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysisDOI 10.1101/2024.11.20.624480
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