Article

A <i>Drosophila</i> Model of Pontocerebellar Hypoplasia Reveals a Critical Role for the RNA Exosome in Neurons

2019-08-08

Abstract excerpt

The RNA exosome is an evolutionarily-conserved ribonuclease complex critically important for precise processing and/or complete degradation of a variety of cellular RNAs. The recent discovery that mutations in genes encoding structural RNA exosome subunits cause tissue-specific diseases makes defining the role of this complex within specific tissues critically important. Mutations in the RNA exosome component 3 (...

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Literature Corpus work: 12bb4fe4-7b28-5643-a1f5-4517cd1b334b
DOI: 10.1101/727693

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