Article

Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single cell resolution: a focus on aging and cancer

2019-03-16

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondria are involved in a number of diverse cellular functions, including energy production, metabolic regulation, apoptosis, calcium homeostasis, cell proliferation and motility as well as free radical generation. Mitochondrial DNA (mtDNA) is present at hundreds to thousands of copies per cell in a tissue-specific manner. Importantly, mtDNA copy number also varies during aging and disease...

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Literature Corpus work: 129d8425-e336-56fe-b348-6b02f29f84d7
DOI: 10.1101/579789

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