Article

Anacardic acid, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549

2013-03-06

Abstract excerpt

<h4>Objective: </h4> and design: The histone acetylation processes, which are believed to play a critical role in the regulation of many inflammatory genes, are reversible and regulated by histone acetyltransferases (HATs), which promote acetylation, and histone deacetylases (HDACs), which promote deacetylation. We studied the effects of lipopolysaccharide (LPS) on histone acetylation and its role in the regulatio...

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Literature Corpus work: 127e56ee-2098-5b55-bf1f-3c10857ec3b0
DOI: 10.12688/f1000research.2-78.v1

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