Article

Epigenetic selection and the DNA methylation signatures of adverse prenatal environments

2018-05-25

Abstract excerpt

Maternal adversity is associated with long-term physiological changes in offspring. These are believed to be mediated through epigenetic mechanisms, including DNA methylation (DNAm). Changes in DNAm are often interpreted as damage or as part of plastic responses of the embryo. We propose that selection on stochastic DNAm differences generated during epigenetic reprogramming after fertilization contributes to the e...

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Literature Corpus work: 127a8d85-0975-5fea-a7aa-f58ff54681b1
DOI: 10.1101/321711

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