Article
An <i>E. coli</i> -based platform for the production and assembly of anellovirus vectors
2024-11-01
Abstract excerpt
Gene therapy offers immense potential for treating various diseases, including cancer, immunodeficiencies, and cardiovascular conditions. The efficacy of gene therapy (GT) largely depends on the vector used for gene delivery. Viral vectors, while effective, pose risks including insertional mutagenesis, immune responses, and high manufacturing costs. Non-viral vectors, although safer and easier to produce, often ex...
Topics
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- Advanced biosensing and bioanalysis techniques
- Bacteriophages and microbial interactions
- CRISPR and Genetic Engineering
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- Viral gastroenteritis research and epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- f51bb1b9-4451-5851-b727-4d43a5dddf86
- DOI
- 10.1101/2024.10.30.621199