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Transcriptome and DNA methylation analysis reveals molecular mechanisms underlying intrahepatic cholangiocarcinoma progression

19 May 2021

Abstract excerpt

Intrahepatic cholangiocarcinoma (iCCA) is an aggressive malignancy with increasing incidence. It has been suggested that DNA methylation drives cancer development. However, the molecular mechanisms underlying iCCA progression and the roles of DNA methylation still remain elusive. In this study, weighted correlation networks were constructed to identify gene modules and hub genes associated with the tumour stage....

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34013637
DOI: 10.1111/jcmm.16615

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