Article

Circasemidian, circadian, and longer-period activity rhythms in caffeine-treated molecular clock deficient cryptochrome (Cry) 1 and Cry 2 double knockout mice

2023-04-15

Abstract excerpt

Mammalian circadian rhythms are driven by the transcriptional-translational feedback loop of clock genes in the hypothalamic suprachiasmatic nucleus. However, chronic methamphetamine treatment induces circadian activity rhythms in arrhythmic animals with suprachiasmatic nucleus lesions or clock gene deletions. Activation of dopaminergic neurotransmission by methamphetamine is considered to induce activity rhythms....

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Literature Corpus work: 12188350-4953-58b6-92ab-4b9b9ae68df9
DOI: 10.22541/au.168154926.62049890/v1

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