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Article

A regulatory pathway linking caffeine action, mood and the diurnal clock.

Neuropharmacology - 1 Aug 2020

Trautmann Charlotte, Burek Dominika, Hübner Christian A, Girault Jean-Antoine, Engmann Olivia

Abstract excerpt

Depression is a leading cause of disability worldwide. Circadian abnormalities and mood changes are symptoms of depression. The psychostimulant caffeine alters wakefulness and alleviates other depression-related symptoms during chronic intake, but the underlying mechanisms are unclear. It is not known, whether and how acute caffeine administration affects mood. Molecular approaches, transgenic mouse models,...

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Identifiers

PMID: 32413367
DOI: 10.1016/j.neuropharm.2020.108133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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