Article
Quantitative differences in the circadian rhythm of locomotor activity and vasopressin and vasoactive intestinal peptide gene expression in the suprachiasmatic nucleus of tau mutant compared to wildtype hamsters.
Brain research - 14 Oct 1996
Scarbrough K, Turek F W
Abstract excerpt
The activity profiles of homozygous tau mutant hamsters bred in our colony exhibit several differences when compared to wildtype golden hamsters. In addition, tau mutant hamsters respond to saturating white light pulses presented between circadian time (CT) 11 and CT 16 with extremely large phase shifts (type 0 resetting) after prolonged time in constant darkness. We measured five parameters of the activity...
Topics
- Animals
- Circadian Rhythm
- Cricetinae
- Darkness
- Homozygote
- In Situ Hybridization
- Light
- Male
- Mesocricetus
- Motor Activity
- Mutation
- RNA, Messenger
- Reference Values
- Suprachiasmatic Nucleus
- Transcription, Genetic