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Article

Disease models of chronic inflammatory airway disease: applications and requirements for clinical trials.

Current opinion in pulmonary medicine - 1 Jan 2014

Diamant Zuzana, Clarke Graham W, Pieterse Herman, Gispert Juan

Abstract excerpt

PURPOSE OF REVIEW: This review will discuss methodologies and applicability of key inflammatory models of respiratory disease in proof of concept or proof of efficacy clinical studies. In close relationship with these models, induced sputum and inflammatory cell counts will be addressed for phenotype-directed drug development. Additionally, important regulatory aspects regarding noninvestigational medicinal...

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Identifiers

PMID: 24231465
DOI: 10.1097/MCP.0000000000000013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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