Back to search

Article

From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL

2019-02-05

Abstract excerpt

While gene expression profiling is commonly used to gain an overview of cellular processes, the identification of upstream processes that drive expression changes remains a challenge. To address this issue, we introduce CARNIVAL, a causal network building tool which derives network architectures from gene expression footprints. CARNIVAL (CAusal Reasoning pipeline for Network identification using Integer VALue prog...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
114213bf-3e30-5138-8f63-c866e608f8be
DOI
10.1101/541888
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVALDOI 10.1101/541888
Select a neighboring publication to make it the new centre.