Article

Expanding large-scale mechanistic models with machine learned associations and big datasets

2022-11-24

Abstract excerpt

Computational models that can explain and predict complex sub-cellular, cellular, and tissue level drug response mechanisms could speed drug discovery and prioritize patient-specific treatments (i.e., precision medicine). Some models are mechanistic: detailed equations describing known (or supposed) physicochemical processes, while some models are statistical/machine learning-based: descriptive correlations that e...

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Literature Corpus work: 727adf85-3a9a-5e57-b27b-33f7d88febf2
DOI: 10.1101/2022.11.21.517431

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