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Induction of innate immunity and its perturbation by influenza viruses

23 Jul 2015

Abstract excerpt

Influenza A viruses (IAV) are highly contagious pathogens causing dreadful losses to human and animal, around the globe. IAVs first interact with the host through epithelial cells, and the viral RNA containing a 5'-triphosphate group is thought to be the critical trigger for activation of effective innate immunity via pattern recognition receptors-dependent signaling pathways. These induced immune responses...

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PMID: 26206138
DOI: 10.1007/s13238-015-0191-z

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